Surface Acoustic Wave Nebulization
Surface acoustic waves are formed by applying alternating current to electrodes that are embedded in a piezoelectric substrate. The propagation of these waves at a certain power can overcome the surface tension of a liquid droplet and induce nebulization and allows it to be seen on a mass spectrometer.
To enhance signal, we couple our SAWN device with a high voltage atmospheric pressure chemical ionization (APCI) needle.
This ionization source is more generic than ESI as it provides more consistent analysis of non polar analytes.
If you want to read more about our SAWN-APCI setup, check out Linxia Song's on Surface Acoustic Wave Nebulization with Atmospheric Pressure Chemical Ionization for Enhanced Ion Signal published in Analytical Chemistry.