DOPC Liposome Synthesis and Characterization

​Currently, we are synthesizing our own DOPC liposomes for use as our model lipid assembly. 

​We are utilizing dynamic light scattering (DLS) and matrix assisted laser desperation ionization (MALDI) as means to analyze the liposomes. MALDI is also being used to disrupt the liposomes lipid bilayer. 

We are doing hdydrogen-deuterium exchange (HDX) on the liposomes to see if differences are viewable on MALDI spectrum. We are trying to optimize incubation and spotting methods of D2O for HDX.

If you have any questions about this project, you can contact Sandra Khalife.